Generation and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome
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چکیده
منابع مشابه
The Mouse SAGE Site: database of public mouse SAGE libraries
The Mouse SAGE Site is a web-based database of all available public libraries generated by the Serial Analysis of Gene Expression (SAGE) from various mouse tissues and cell lines. The database contains mouse SAGE libraries organized in a uniform way and provides web-based tools for browsing, comparing and searching SAGE data with reliable tag-to-gene identification. A modified approach based on...
متن کاملModeling and Analysis of SAGE Libraries
A Serial Analysis of Gene Expression (SAGE) library is a collection of thousands of small DNA “tags”, each of which represents a distinct mRNA transcript. Existing methods have been proposed for analyzing single library data (i.e., one library per group) or one tag at a time. The practice of lumping all libraries together (in a multi-library setting) to form a “mega” library for each group is o...
متن کاملFull transcriptome analysis of rhabdomyosarcoma, normal, and fetal skeletal muscle: statistical comparison of multiple SAGE libraries.
Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma in children. Improved treatment strategies have increased overall survival, but the response of approximately one-third of the patients is still poor. To increase the knowledge of RMS pathogenesis, we performed the first full transcriptome analysis of RMS using serial analysis of gene expression (SAGE). With a G-test for the simult...
متن کاملDeep SAGE analysis of the Caenorhabditis elegans transcriptome
We employed the Tag-seq technique to generate global transcription profiles for different strains and life stages of the nematode C. elegans. Tag-seq generates cDNA tags as does Serial Analysis of Gene Expression (SAGE), but the method yields a much larger number of tags, generating much larger data sets than SAGE. We examined differences in the performance of SAGE and Tag-seq by comparing gene...
متن کاملA human glomerular SAGE transcriptome database
BACKGROUND To facilitate in the identification of gene products important in regulating renal glomerular structure and function, we have produced an annotated transcriptome database for normal human glomeruli using the SAGE approach. DESCRIPTION The database contains 22,907 unique SAGE tag sequences, with a total tag count of 48,905. For each SAGE tag, the ratio of its frequency in glomeruli ...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2004
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1207337